• Indian scientists revealed after genome sequencing, the same variant found in two different travelers
  • In January this year, passengers had returned from Brazil and UK.
  • Scientists warn, this variant is more serious and starts reducing antibodies

After Alpha, Beta, Gamma, and Delta, another new corona variant has been revealed in India, which can reduce the weight of the patient in seven days. This variant of the virus was first found in Brazil but from there only one variant was confirmed to have arrived in India. Now scientists have clarified that not one but two variants have come to India from Brazil and this second variant B.1.1.28.2 is much faster.

Tests in Syrian hamsters (a species of rat) have shown that the variant can be detected within seven days of being infected. This variant can cause rapid body weight loss and, like Delta, it can also be more severe and have reduced antibody potential.

Dr. Pragya Yadav of the National Institute of Virology (NIV), Pune, said that the B.1.1.28.2 variant was found in two people who came from outside. After doing genome sequencing, we also tested it so that we can know about its effect. Till now there are not many cases of this in India. Whereas the Delta variant is getting the most. However, vigilance is very important as it also lowers the level of antibodies, due to which the risk of getting infected again increases.

He told that in January this year, the P1 lineage of coronavirus was detected which is also known as 20J/501YV3. Variations were observed on 17 types of spike proteins, including N501Y, E484K and K417N. During this time the P2 lineage also came to India, which is now known. The spike protein of this virus has an amino acid change called E484K but does not have changes named N501Y and K417N. Since the government has made genome sequencing of samples of all travelers who have returned from foreign travel mandatory. That’s why we also got to know about the new variant.

Three out of nine Syrian hamsters died
Samples of two people, 69 and 26, who had returned from foreign travel, were sequenced. Both these patients were not symptomatic till the time of recovery, but after sequencing their samples, when the B.1.1.28.2 variant was detected, it was tested on nine Syrian hamsters for seven days. Of these, three died due to increasing infection in the internal part of the body. During this, the pathology of the lung was also found and information has also been received about the low level of antibodies.

Different results on human-Syrian hamsters
In this study, it has been found that two people who got this variant were asymptomatic but when this variant infected Syrian hamsters, the severity was known. According to scientists, most of the tests for coronavirus are being done on Syrian hamsters. In such a situation, it would not be wrong to say that if the cases related to B.1.1.28.2 increase, then its effect on humans can be very serious.

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